Orgasmic Anhedonia/ PDOD: Causes

Content Written By: Michael Perelman, PhD

It is thought that men with pleasure dissociative orgasmic disorder or orgasmic anhedonia have a dysfunction in regulation of the brain neurochemical dopamine in the region of the brain’s reward center, the nucleus accumbens. This region of the brain is thought to play an important role in reward, laughter, pleasure, addiction, and music.

Pleasure dissociative orgasmic disorder or orgasmic anhedonia may be caused by psychologic issues such as depression or drug addiction, or by physiologic issues such as high levels of prolactin, low levels of testosterone, use of medications such as SSRI antidepressants, chronic medical problems such as spinal cord injury, and chronic fatigue syndrome.

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